Dynamic Coronary Artery Phantom Test System Emulating Cardiac and Respiratory Motion
Gutierrez Valenzuela, J. (2023). Dynamic Coronary Artery Phantom Test System Emulating Cardiac and Respiratory Motion. Thesis.
The continuous innovation and development of cardiovascular disease diagnosis and treatment devices entail the need for proper validation testbeds, such as the anatomically and bio-mechanically correct testing platforms commonly referred to as “Phantoms.” Besides validation, Phantoms are a very effective tool used to perform simulations and fine-tune medical devices where sometimes motion is also needed for a more accurate simulation. Computer-aided design and 3D printing technologies are cost-effective tools to develop controlled motion systems. In this work, a Dynamic Phantom Test System was designed, prototyped, and tested to emulate the impact of Cardiac and Respiratory Motion on the coronary artery. A stenotic coronary artery phantom was developed in three different versions: PVA-C, 3D printed material (TangoPlus) and composite material (TangoPlus & VeroWhite). A hemodynamic circuit representing the circulatory system was developed and attached to the phantom and a pulsatile pump. Finally, a cam mechanism was incorporated to generate the movement of the coronary artery in the superior-inferior direction, with the capacity to exchange movement profiles such as heartbeat, respiration and their combination. The results showed an impact on the pressure curve. However, the FFR and dPR readings during a pressure guidewire angiogram showed no discrepancies between the static and moving hemodynamic circuit.